CRISPR gene editing to cure HIV? It’s now in clinical trials

CRISPR gene editing to cure HIV? It’s now in clinical trials

Kezia Parkins | 
The US Food and Drug Administration (FDA) has given the nod for Excision BioTherapeutics to begin trials testing CRISPR gene ...
‘Junk DNA’: The 98% of the human genome that does not encode proteins is often called useless — but the reality is more complicated

‘Junk DNA’: The 98% of the human genome that does not encode proteins is often called useless — but the reality is more complicated

Jake Buehler | 
The human genome has three billion base pairs in its DNA, but only about 2% of them encode proteins. The ...
DNA in space: First CRISPR gene-editing study by astronauts opens door to future experimentation

DNA in space: First CRISPR gene-editing study by astronauts opens door to future experimentation

Ailsa Harvey | 
The first CRISPR experiment to take place in space shows that DNA can repair itself in microgravity.  As part of ...
CRISPR opens the door to altering nature. What could go right — and wrong?

CRISPR opens the door to altering nature. What could go right — and wrong?

Hayley Bennett | 
Gene editing today usually means making precise changes using CRISPR, a bacterial DNA-cutting system adopted by scientists. It works within ...
CRISPR, fluorescent proteins, optogenetics: Three life-enhancing technologies inspired by nature

CRISPR, fluorescent proteins, optogenetics: Three life-enhancing technologies inspired by nature

Marc Zimmer | 
Watson and Crick, Schrödinger and Einstein all made theoretical breakthroughs that have changed the world’s understanding of science. Today big, game-changing ideas are less ...
60% of elderly people have hearing problems. Here’s how gene editing and other cutting-edge techniques could restore the inner ear

60% of elderly people have hearing problems. Here’s how gene editing and other cutting-edge techniques could restore the inner ear

Hearing loss is one of the most common disabilities in the United States. It can be caused by the effects ...
Kenya is emerging as a major hub of CRISPR biomedical research in Africa

Kenya is emerging as a major hub of CRISPR biomedical research in Africa

Joseph Maina | 
Kenyan scientist Dr Hussein Abkallo wound up in the sophisticated world of Crispr Cas9 almost by chance, unaware that the ...
How CRISPR gene editing will revolutionize medicine

How CRISPR gene editing will revolutionize medicine

John Schulthesis | 
Already, there have been hundreds of proposed applications for CRISPR, some more interesting and others more problematic. A few examples ...
‘Designing’ cats to be less allergenic? Gene editing provides a solution

‘Designing’ cats to be less allergenic? Gene editing provides a solution

Stacey Burling | 
Solutions for people who want to be around cats despite allergies are labor-intensive, of questionable value, and sometimes defy common ...
How genes from other species can open the door to human colonization of the far reaches of the universe

How genes from other species can open the door to human colonization of the far reaches of the universe

Ian Taylor | 
[Geneticist Christopher Mason has developed] a “500-year plan for the survival of the human species on Earth, in space, and ...
The world of ‘designer DNA’ meets the challenge of intractable genetic disorders. Here’s how that story may play out

The world of ‘designer DNA’ meets the challenge of intractable genetic disorders. Here’s how that story may play out

Carolyn Barber | 
[T]he cutting-edge world of innovative genomic therapies is once again in the midst of explosive change—and designer DNA lies at ...
Biryani boost: Raft of gene editing innovations can improve rice quality and flavors

Biryani boost: Raft of gene editing innovations can improve rice quality and flavors

Today, biryani is a staple in millions of kitchens around the world. And yet, no two are alike. Myriad add-ons ...
CRISPR gene editing debuts in space, as astronauts study how DNA repairs itself from cosmic radiation

CRISPR gene editing debuts in space, as astronauts study how DNA repairs itself from cosmic radiation

Amirah Al Idrus | 
Space radiation has long been a concern for astronauts living beyond Earth’s protective atmosphere—it can damage DNA, leading to cancer ...
With treatments for COVID still elusive, CRISPR offers promise in preliminary tests

With treatments for COVID still elusive, CRISPR offers promise in preliminary tests

Rachel Rettner | 
Scientists have harnessed CRISPR gene-editing technology to block the replication of the novel coronavirus in human cells — an approach ...
Viewpoint: Might CRISPR gene editing ‘unleash dangerous mutants, designer babies and new weapons of mass destruction?’

Viewpoint: Might CRISPR gene editing ‘unleash dangerous mutants, designer babies and new weapons of mass destruction?’

John Lauerman | 
Mankind has been manipulating genetics since early civilizations realized that certain traits of crops, animals and humans themselves were hereditary ...
Video: Curious about the full implications of the CRISPR gene editing revolution? Here’s a primer

Video: Curious about the full implications of the CRISPR gene editing revolution? Here’s a primer

Andrea Gawrylewski, Michael Tabb | 
With CRISPR, a group of enzymes recognize certain repeats, and break the DNA there to insert important information in the ...
Saving the world — or possibly destroying it? What does the future of CRISPR genetic engineering portend?

Saving the world — or possibly destroying it? What does the future of CRISPR genetic engineering portend?

Sherryn Groch | 
In the past 70 years, we have uncovered the structure of DNA, the blueprint of life, built machines to read ...
Setting ethical limits on human gene editing after fall of 14-day barrier

Setting ethical limits on human gene editing after fall of 14-day barrier

Delthia Ricks | 
Quick, accurate and easy-to-use, CRISPR-Cas9 has made genomic editing more efficient—but at the same time has made human germline editing ...
WHO restates opposition to gene-editing live human embryos but endorses other forms of genome modification

WHO restates opposition to gene-editing live human embryos but endorses other forms of genome modification

Megan Molteni | 
[July 12,] a World Health Organization advisory committee called on the world’s largest public health authority to stand by the ...
WHO proposes global registry and whistle-blowing mechanism to curb unethical and unsafe human gene editing abuses

WHO proposes global registry and whistle-blowing mechanism to curb unethical and unsafe human gene editing abuses

The World Health Organization issued new recommendations [July 12] on human genome editing, calling for a global registry to track ...
Intellia’s disease-eradicating CRISPR tool is injected directly into the bloodstream. Here’s why that’s such a big deal

Intellia’s disease-eradicating CRISPR tool is injected directly into the bloodstream. Here’s why that’s such a big deal

Kristen Houser | 
CRISPR gives us the ability to correct genetic mutations, and given that such mutations are responsible for more than 6,000 ...
Why sickle cell disease is a perfect target candidate for CRISPR gene editing

Why sickle cell disease is a perfect target candidate for CRISPR gene editing

Katherine Blesie | 
When the gene-editing technology CRISPR/Cas9 was discovered in 2012 by Berkeley biochemist Jennifer Doudna and collaborator Emmanuelle Charpentier, it changed ...
Here’s an update on the (quixotic?) CRISPR gene editing project to revive the defunct woolly mammoth

Here’s an update on the (quixotic?) CRISPR gene editing project to revive the defunct woolly mammoth

Eric James Beyer | 
As CRISPR allows scientists to splice individual genes that program for specific characteristics into the genome of living species, it ...
CRISPR milestone: Crippling transthyretin amyloidosis disease now treatable through gene editing, paving way for addressing other genetic diseases

CRISPR milestone: Crippling transthyretin amyloidosis disease now treatable through gene editing, paving way for addressing other genetic diseases

Rob Stein | 
[65-year-old Patrick] Doherty found out he had a rare, but devastating inherited disease — known as transthyretin amyloidosis — that ...
CRISPR gene editing on the cusp of adding new gene drive tools to control disease-carrying mosquitoes

CRISPR gene editing on the cusp of adding new gene drive tools to control disease-carrying mosquitoes

[D]espite decades of effort, vaccines have, for many [diseases like malaria and dengue], proved tricky to develop. Better, then, to ...
Viewpoint: 'Magic promised by genetically pruning ‘defective’ embryos has fairy-dusted the eyes of even the most intelligent’ — Maybe it’s time to hit the pause button

Viewpoint: ‘Magic promised by genetically pruning ‘defective’ embryos has fairy-dusted the eyes of even the most intelligent’ — Maybe it’s time to hit the pause button

Barbara Pfeffer Billauer | 
Advances in genetics have been revolutionized in the last few years. First came CRISPR, which can edit single genes, possibly ...
Viewpoint: Patenting human embryo gene editing? Two rival universities push the ethical and legal debate

Viewpoint: Patenting human embryo gene editing? Two rival universities push the ethical and legal debate

Pete Shanks | 
Two prominent groups of scientists, and two major American universities, are trying to patent methods for editing human embryos, with ...
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